The US-Taiwan cooperative research project among NCREE, National Taiwan University, University of California, San Diego, and University of Michigan, Ann Arbor is supported by the Ministry of Science and Technology (108-2625-M-002-003), Taiwan. Additional support is provided by a NIST under Award 70NANB171TZ91 to University of Michigan and UC San Diego. The participants in this work include Director C. C Chou and team members of NCREE, Professors C. M. Uang and G. Mosqueda of UCSD, and Professors S. El-Tawil and J. P. McCormick of University of Michigan. The work was focused on the seismic behavior of the first-story steel columns in building frames under large axial load and lateral cyclic drifts. To reflect realistic column boundary conditions at both ends, several half-scale, two-story steel subassemblage frames with a single column and steel beams at two floors were tested to evaluate the cyclic behavior of the first-story columns. The inflection point, shortening and plastic hinge formation in the two-story columns vary significantly compared to typical isolated column tests with fixed-fixed boundary condition at both ends. The research works are published in the 17th World Conference on Earthquake Engineering, Japan, 2021, and the 12th National Conference on Earthquake Engineering, USA, 2022.